APOE Knockout LLC-MK2 Cell Line
Cat.No.:
EDJ-KZ546
Species:
Rhesus Monkey
Cell Name:
LLC-MK2
Gene:
APOE
Gene ID:
348
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ546 |
|---|---|
| Product Name | APOE Knockout LLC-MK2 Cell Line |
| Cell Line | LLC-MK2 |
| Cellosaurus ID | CVCL_3009 |
| Cell Line Synonyms | Llc-Mk2, LLC-MK-2, LLC-MK2 Original, LLCMK2, LLcMK2, Lilly Laboratories Culture-Monkey Kidney 2, MK2 |
| Gene | APOE |
| Gene Synonyms | AD2|APO-E|ApoE4|LDLCQ5|LPG |
| Summary |
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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