Overview
Cell Fate Determination
Study the molecular mechanisms that govern stem cell differentiation, lineage commitment and cell identity maintenance using CRISPR-engineered cell models.
What is Cell Fate Determination ?
Cell fate determination is the process by which cells adopt specific identities during development and tissue homeostasis. It is regulated by transcription factor networks, signaling gradients (Notch, Wnt, BMP) and epigenetic landscapes. Understanding and manipulating cell fate is fundamental to regenerative medicine and cancer stem cell biology.
Key Research Applications
Lineage tracing
Master transcription factor annlysis
Directed differentiation of pluripotent stem cells
Cell fate reprogramming (iPSC
transdifferentiation)
Single-cell transcriptomic fate mapping
Products
Featured/Popular Targets
ALL
TP53
Rb1
MYC
NOTCH2
NOTCH3
WNT5A
CTNNB1
DNMT1
GATA2
GATA3
FOXA1
FOXA2
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| TP53 Knockout HCT 116 Cell Line | EDC07854 | Human | 7157 | Details Get a Quote |
| CTNNB1 Knockout HCT 116 Cell Line | EDJ-KQ22 | Human | 1499 | Details Get a Quote |
| CTNNB1 Knockout HEK293 Cell Line | EDC07547 | Human | 1499 | Details Get a Quote |
| WNT5A Knockout HEK293 Cell Line | EDJ-KQ354 | Human | 7474 | Details Get a Quote |
| NOTCH2 Knockout HEK293 Cell Line | EDJ-KQ436 | Human | 4853 | Details Get a Quote |
| NOTCH3 Knockout HEK293 Cell Line | EDJ-KQ437 | Human | 4854 | Details Get a Quote |
| GATA3 Knockout HEK293 Cell Line | EDJ-KQ1017 | Human | 2625 | Details Get a Quote |
| FOXA1 Knockout HEK293 Cell Line | EDJ-KQ2840 | Human | 3169 | Details Get a Quote |
| FOXA2 Knockout HEK293 Cell Line | EDJ-KQ2898 | Human | 3170 | Details Get a Quote |
| GATA2 Knockout HEK293 Cell Line | EDJ-KQ4687 | Human | 2624 | Details Get a Quote |
| RB1 Knockout HEK293 Cell Line | EDC07586 | Human | 5925 | Details Get a Quote |
| TP53 Knockout HEK293 Cell Line | EDJ-KQ17910 | Human | 7157 | Details Get a Quote |
| TP53 Knockout hTERT-RPE1 Cell Line | EDC00205 | Human | 7157 | Details Get a Quote |
| CTNNB1 Knockout A-549 Cell Line | EDJ-KQ17963 | Human | 1499 | Details Get a Quote |
| NOTCH3 Knockout HeLa Cell Line | EDJ-KQ18002 | Human | 4854 | Details Get a Quote |
Displaying Records 1 To 15 Of 116 Records
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