Overview
Mitochondrial Function
Study mitochondrial respiration, dynamics, biogenesis, mitophagy and mitochondrial dysfunction in disease using CRISPR-engineered cell models.
What is Mitochondrial Function ?
Mitochondria are central organelles for ATP production, calcium buffering, lipid metabolism and apoptosis. Mitochondrial dysfunction is implicated in neurodegeneration, metabolic disease and aging. Key processes include oxidative phosphorylation, mitochondrial fusion/fission, and quality control via mitophagy. CRISPR tools enable precise investigation of nuclear-encoded mitochondrial genes.
Key Research Applications
Oxygen consumption rate (OCR) measurement
Mitochondrial membrane potential assays
Mitophagy flux reporter systems
mtDNA maintenance gene studies
Mitochondrial disease variant validation
Products
Featured/Popular Targets
ALL
SLC25A1
SLC25A3
SLC25A4
SLC25A5
SLC25A6
SLC25A10
SLC25A11
SLC25A12
SLC25A13
SLC25A14
SLC25A15
SLC25A16
SLC25A17
SLC25A18
SLC25A19
SLC25A20
SLC25A21
SLC25A22
SLC25A23
SLC25A24
SLC25A25
SLC25A26
SLC25A27
SLC25A28
SLC25A29
SLC25A30
SLC25A32
SLC25A33
SLC25A34
SLC25A35
SLC25A36
SLC25A37
SLC25A38
SLC25A39
SLC25A40
SLC25A42
SLC25A43
SLC25A44
SLC25A45
SLC25A46
SLC25A51
MTCH1
MTCH2
LETM1
LETM2
TOMM7
TOMM70
PINK1
PARK7
PRKN
CHCHD3
CHCHD6
NDUFS4
GPD2
IDH2
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| SLC25A5 Knockout HEK293T Cell Line | EDJ-KQ01 | Human | 292 | Details Get a Quote |
| PARK7 Knockout HT22 Cell Line | EDJ-KQ72 | Mouse | 57320 | Details Get a Quote |
| PARK7 Knockout HEK293 Cell Line | EDJ-KQ969 | Human | 11315 | Details Get a Quote |
| SLC25A4 Knockout HEK293 Cell Line | EDJ-KQ1627 | Human | 291 | Details Get a Quote |
| SLC25A6 Knockout HEK293 Cell Line | EDJ-KQ1628 | Human | 293 | Details Get a Quote |
| CHCHD6 Knockout HEK293 Cell Line | EDJ-KQ1903 | Human | 84303 | Details Get a Quote |
| SLC25A21 Knockout HEK293 Cell Line | EDJ-KQ1981 | Human | 89874 | Details Get a Quote |
| MTCH2 Knockout HEK293 Cell Line | EDC07966 | Human | 23788 | Details Get a Quote |
| TOMM7 Knockout HEK293 Cell Line | EDJ-KQ2390 | Human | 54543 | Details Get a Quote |
| MTCH1 Knockout HEK293 Cell Line | EDJ-KQ2576 | Human | 23787 | Details Get a Quote |
| SLC25A29 Knockout HEK293 Cell Line | EDJ-KQ2594 | Human | 123096 | Details Get a Quote |
| SLC25A13 Knockout HEK293 Cell Line | EDJ-KQ2598 | Human | 10165 | Details Get a Quote |
| SLC25A42 Knockout HEK293 Cell Line | EDJ-KQ2661 | Human | 284439 | Details Get a Quote |
| PRKN Knockout HEK293 Cell Line | EDJ-KQ3360 | Human | 5071 | Details Get a Quote |
| PINK1 Knockout HEK293 Cell Line | EDJ-KQ3426 | Human | 65018 | Details Get a Quote |
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