Overview
AMPK Signaling
Study AMPK pathway regulation, energy homeostasis, metabolic stress responses and cancer-associated AMPK functions using CRISPR-engineered cell models.
What is AMPK Signaling ?
AMP-activated protein kinase (AMPK) is a central energy sensor that maintains metabolic homeostasis by activating catabolic pathways and inhibiting anabolism during low energy states. AMPK signaling intersects with metabolism, autophagy and cell growth, with dual roles in cancer as a context-dependent tumor suppressor or survival factor.
Key Research Applications
AMPK activator/inhibitor screening
Metabolic stress response assays
Autophagy regulation studies
Tumor metabolism analysis
Energy homeostasis target discovery
Products
Featured/Popular Targets
ALL
PRKAA1
PRKAA2
PRKAB1
PRKAG1
PRKAG2
CAMKK2
TSC2
SREBF1
SREBF2
ACACA
ACACB
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| PRKAA1 Knockout HEK293 Cell Line | EDJ-KQ860 | Human | 5562 | Details Get a Quote |
| PRKAA2 Knockout HEK293 Cell Line | EDJ-KQ861 | Human | 5563 | Details Get a Quote |
| SREBF2 Knockout HEK293 Cell Line | EDJ-KQ1125 | Human | 6721 | Details Get a Quote |
| PRKAB1 Knockout HEK293 Cell Line | EDJ-KQ1446 | Human | 5564 | Details Get a Quote |
| PRKAG1 Knockout HEK293 Cell Line | EDJ-KQ1449 | Human | 5571 | Details Get a Quote |
| PRKAG2 Knockout HEK293 Cell Line | EDJ-KQ1451 | Human | 51422 | Details Get a Quote |
| CAMKK2 Knockout HEK293 Cell Line | EDJ-KQ1857 | Human | 10645 | Details Get a Quote |
| SREBF1 Knockout HEK293 Cell Line | EDJ-KQ1869 | Human | 6720 | Details Get a Quote |
| ACACB Knockout HEK293 Cell Line | EDJ-KQ1874 | Human | 32 | Details Get a Quote |
| TSC2 Knockout HEK293 Cell Line | EDJ-KQ17912 | Human | 7249 | Details Get a Quote |
| TSC2 Knockout HCT 116 Cell Line | EDJ-KQ18154 | Human | 7249 | Details Get a Quote |
| PRKAB1 Knockout A-549 Cell Line | EDJ-KQ20996 | Human | 5564 | Details Get a Quote |
| PRKAB1 Knockout HCT 116 Cell Line | EDJ-KQ20997 | Human | 5564 | Details Get a Quote |
| PRKAB1 Knockout HeLa Cell Line | EDJ-KQ20998 | Human | 5564 | Details Get a Quote |
| PRKAG1 Knockout A-549 Cell Line | EDJ-KQ21001 | Human | 5571 | Details Get a Quote |
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