Overview
Stem Cell Pluripotency
Study pluripotency networks (OCT4, SOX2, NANOG), self-renewal and differentiation using CRISPR-engineered pluripotent stem cells.
What is Stem Cell Pluripotency ?
Pluripotency is the ability of a stem cell to differentiate into all three germ layers. It is maintained by a core transcriptional network including OCT4, SOX2 and NANOG, and regulated by signaling pathways (FGF, TGF-β, Wnt). CRISPR tools enable dissection of the pluripotency circuit and its dissolution during differentiation, with applications in regenerative medicine.
Key Research Applications
Self-renewal and colony formation assays
Directed differentiation potency testing
Reprogramming efficiency studies
Naïve vs primed pluripotency analysis
Products
Featured/Popular Targets
ALL
MYC
KLF4
STAT3
SMAD1
SMAD3
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| SMAD1 Knockout HEK293 Cell Line | EDJ-KQ399 | Human | 4086 | Details Get a Quote |
| SMAD3 Knockout HEK293 Cell Line | EDJ-KQ400 | Human | 4088 | Details Get a Quote |
| STAT3 Knockout HEK293 Cell Line | EDJ-KQ903 | Human | 6774 | Details Get a Quote |
| KLF4 Knockout HEK293 Cell Line | EDJ-KQ2519 | Human | 9314 | Details Get a Quote |
| SMAD3 Knockout HeLa Cell Line | EDJ-KQ17985 | Human | 4088 | Details Get a Quote |
| STAT3 Knockout HeLa Cell Line | EDJ-KQ18072 | Human | 6774 | Details Get a Quote |
| STAT3 Knockout A-549 Cell Line | EDJ-KQ21087 | Human | 6774 | Details Get a Quote |
| STAT3 Knockout HCT 116 Cell Line | EDJ-KQ21089 | Human | 6774 | Details Get a Quote |
| KLF4 Knockout A-549 Cell Line | EDJ-KQ23130 | Human | 9314 | Details Get a Quote |
| KLF4 Knockout HeLa Cell Line | EDJ-KQ23132 | Human | 9314 | Details Get a Quote |
| SMAD1 Knockout A-549 Cell Line | EDJ-KQ18634 | Human | 4086 | Details Get a Quote |
| SMAD1 Knockout HCT 116 Cell Line | EDJ-KQ18635 | Human | 4086 | Details Get a Quote |
| SMAD1 Knockout HeLa Cell Line | EDJ-KQ18636 | Human | 4086 | Details Get a Quote |
| SMAD3 Knockout A-549 Cell Line | EDJ-KQ18637 | Human | 4088 | Details Get a Quote |
| SMAD3 Knockout HCT 116 Cell Line | EDJ-KQ18638 | Human | 4088 | Details Get a Quote |
Displaying Records 1 To 15 Of 25 Records
