Overview
Vesicle Trafficking
Study COPII/COPI vesicle coat assembly, SNARE-mediated fusion, Rab GTPase regulation and endosomal/lysosomal trafficking using CRISPR-engineered cell models.
What is Vesicle Trafficking ?
Vesicle trafficking mediates protein and lipid transport between membrane-bound compartments. COPII vesicles bud from the ER, COPI from the Golgi, and clathrin from the plasma membrane/TGN. Rab GTPases and SNARE proteins ensure specificity of targeting and fusion. Defects in vesicle trafficking cause neurological disorders, immune deficiencies and cancer.
Key Research Applications
VSVG-GFP trafficking synchronization assays
Rab GTPase knockout/knockin localization studies
SNARE complex assembly and fusion assays
Endosomal sorting complex (ESCRT) functional analysis
Secretory and endocytic pathway intersection analysis
Products
Featured/Popular Targets
ALL
RAB5A
RAB7A
RAB27A
RAB27B
RAB2A
RAB4A
RAB6A
RAB8A
RAB12
RAB13
RAB14
RAB20
RAB21
RAB31
RAB32
RAB3A
STX7
SNAP23
SNAP25
VAMP1
SYT2
CLINT1
OPTN
VPS13A
VPS13C
VAC14
FIG4
SYNJ1
SYNJ2
PITPNB
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| OPTN Knockout HEK293T Cell Line | EDJ-KQ197 | Human | 10133 | Details Get a Quote |
| SYNJ2 Knockout HEK293 Cell Line | EDJ-KQ1006 | Human | 8871 | Details Get a Quote |
| RAB8A Knockout HEK293 Cell Line | EDJ-KQ1185 | Human | 4218 | Details Get a Quote |
| RAB5A Knockout HEK293 Cell Line | EDJ-KQ1282 | Human | 5868 | Details Get a Quote |
| SYNJ1 Knockout HEK293 Cell Line | EDJ-KQ1656 | Human | 8867 | Details Get a Quote |
| RAB2A Knockout HEK293 Cell Line | EDJ-KQ1880 | Human | 5862 | Details Get a Quote |
| RAB14 Knockout HEK293 Cell Line | EDJ-KQ1884 | Human | 51552 | Details Get a Quote |
| OPTN Knockout HEK293 Cell Line | EDJ-KQ2061 | Human | 10133 | Details Get a Quote |
| VAMP1 Knockout HEK293 Cell Line | EDJ-KQ2330 | Human | 6843 | Details Get a Quote |
| RAB31 Knockout HEK293 Cell Line | EDJ-KQ2369 | Human | 11031 | Details Get a Quote |
| RAB6A Knockout HEK293 Cell Line | EDJ-KQ2934 | Human | 5870 | Details Get a Quote |
| RAB7A Knockout HEK293 Cell Line | EDJ-KQ3022 | Human | 7879 | Details Get a Quote |
| RAB27A Knockout HEK293 Cell Line | EDJ-KQ3826 | Human | 5873 | Details Get a Quote |
| RAB27B Knockout HEK293 Cell Line | EDJ-KQ3920 | Human | 5874 | Details Get a Quote |
| FIG4 Knockout HEK293 Cell Line | EDJ-KQ3972 | Human | 9896 | Details Get a Quote |
Displaying Records 1 To 15 Of 143 Records
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