Overview
Drug Resistance
Study mechanisms of cancer drug resistance, therapeutic adaptation and resistance-associated signaling pathways using CRISPR-engineered cell models.
What is Drug Resistance ?
Drug resistance occurs when cancer cells adapt to therapeutic pressure and develop the ability to survive treatment. These mechanisms involve genetic alterations, pathway activation, drug efflux regulation, and changes in cellular metabolism. Understanding resistance mechanisms is critical for developing next-generation therapies and improving treatment strategies.
Key Research Applications
Anticancer drug resistance studies
Resistance mechanism discovery
Combination therapy screening
Target validation studies
Products
Featured/Popular Targets
ALL
ABCB1
ABCG2
ABCC1
MGMT
BCL2L2
SLC22A1
SLC47A1
Product name Cat.No. Species Gene ID
ABCC1 Knockout HEK293 Cell Line EDC07524 Human 4363 Details Get a Quote
ABCG2 Knockout HEK293 Cell Line EDC07525 Human 9429 Details Get a Quote
MGMT Knockout HEK293 Cell Line EDJ-KQ3115 Human 4255 Details Get a Quote
ABCB1 Knockout HEK293 Cell Line EDC07523 Human 5243 Details Get a Quote
SLC22A1 Knockout HEK293 Cell Line EDJ-KQ5796 Human 6580 Details Get a Quote
SLC47A1 Knockout HEK293 Cell Line EDJ-KQ15346 Human 55244 Details Get a Quote
SLC22A1 Knockout A-549 Cell Line EDJ-KQ29210 Human 6580 Details Get a Quote
SLC47A1 Knockout A-549 Cell Line EDJ-KQ46075 Human 55244 Details Get a Quote
SLC47A1 Knockout HeLa Cell Line EDJ-KQ44856 Human 55244 Details Get a Quote
ABCC1 Knockout HeLa Cell Line EDJ-KQ20280 Human 4363 Details Get a Quote
ABCC1 Knockout A-549 Cell Line EDJ-KQ21627 Human 4363 Details Get a Quote
ABCC1 Knockout HCT 116 Cell Line EDJ-KQ21628 Human 4363 Details Get a Quote
ABCG2 Knockout HCT 116 Cell Line EDJ-KQ22300 Human 9429 Details Get a Quote
ABCG2 Knockout A-549 Cell Line EDJ-KQ23672 Human 9429 Details Get a Quote
MGMT Knockout A-549 Cell Line EDJ-KQ24460 Human 4255 Details Get a Quote
Displaying Records 1 To 15 Of 37 Records
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