Overview
Oxidative Stress & Redox
Study reactive oxygen species (ROS) production, antioxidant defense, redox signaling and oxidative damage mechanisms using CRISPR-engineered cell models.
What is Oxidative Stress & Redox ?
Oxidative stress results from an imbalance between ROS production and antioxidant capacity, leading to damage of lipids, proteins and DNA. It is implicated in aging, cancer, neurodegeneration and cardiovascular disease. Key regulators include NRF2, SODs and glutathione systems. CRISPR tools help dissect the genetic control of redox homeostasis.
Key Research Applications
ROS detection and quantification assays
NRF2/KEAP1 pathway reporter systems
Glutathione level measurement
Antioxidant gene knockout screening
Oxidative damage biomarker analysis
Products
Featured/Popular Targets
ALL
GSR
NFE2L2
KEAP1
TXNIP
SRXN1
BLVRB
NOS2
NOS1
NOS3
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| NOS3 Knockout HEK293 Cell Line | EDJ-KQ840 | Human | 4846 | Details Get a Quote |
| NOS1 Knockout HEK293 Cell Line | EDJ-KQ844 | Human | 4842 | Details Get a Quote |
| NOS2 Knockout HEK293 Cell Line | EDJ-KQ1428 | Human | 4843 | Details Get a Quote |
| GSR Knockout HEK293 Cell Line | EDJ-KQ3546 | Human | 2936 | Details Get a Quote |
| TXNIP Knockout HEK293 Cell Line | EDJ-KQ3658 | Human | 10628 | Details Get a Quote |
| BLVRB Knockout HEK293 Cell Line | EDJ-KQ4136 | Human | 645 | Details Get a Quote |
| SRXN1 Knockout HEK293 Cell Line | EDJ-KQ9816 | Human | 140809 | Details Get a Quote |
| NFE2L2 Knockout HEK293 Cell Line | EDC90189 | Human | 4780 | Details Get a Quote |
| NFE2L2 Knockout A-549 Cell Line | EDC90777 | Human | 4780 | Details Get a Quote |
| NFE2L2 Knockout HCT 116 Cell Line | EDJ-KQ44611 | Human | 4780 | Details Get a Quote |
| NFE2L2 Knockout HeLa Cell Line | EDJ-KQ44612 | Human | 4780 | Details Get a Quote |
| NOS3 Knockout HCT 116 Cell Line | EDJ-KQ19625 | Human | 4846 | Details Get a Quote |
| TXNIP Knockout HeLa Cell Line | EDJ-KQ24253 | Human | 10628 | Details Get a Quote |
| GSR Knockout A-549 Cell Line | EDJ-KQ25398 | Human | 2936 | Details Get a Quote |
| GSR Knockout HCT 116 Cell Line | EDJ-KQ25399 | Human | 2936 | Details Get a Quote |
Displaying Records 1 To 15 Of 47 Records
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