Overview
Glucose Metabolism
Study glucose uptake, glycolysis, gluconeogenesis, TCA cycle and their roles in energy homeostasis and metabolic diseases using CRISPR-engineered cell models.
What is Glucose Metabolism ?
Glucose metabolism encompasses the pathways that break down glucose to produce energy (glycolysis, TCA cycle, oxidative phosphorylation) and synthesize it when needed (gluconeogenesis). Dysregulation is central to diabetes, obesity and cancer. Cancer cells often display the Warburg effect (aerobic glycolysis), which is exploited for metabolic therapy development.
Key Research Applications
Glycolytic flux measurement
Glucose transporter (GLUT) screening
Insulin-regulated glucose uptake assays
Gluconeogenic gene knockout studies
Cancer cell metabolic vulnerability profiling
Products
Featured/Popular Targets
ALL
SLC2A1
SLC2A2
SLC2A3
SLC2A4
HK2
PKM
G6PD
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| SLC2A1 Knockout HEK293 Cell Line | EDC08016 | Human | 6513 | Details Get a Quote |
| HK2 Knockout HEK293 Cell Line | EDJ-KQ1507 | Human | 3099 | Details Get a Quote |
| SLC2A4 Knockout HEK293 Cell Line | EDJ-KQ1523 | Human | 6517 | Details Get a Quote |
| SLC2A3 Knockout HEK293 Cell Line | EDJ-KQ3905 | Human | 6515 | Details Get a Quote |
| SLC2A2 Knockout HEK293 Cell Line | EDJ-KQ5759 | Human | 6514 | Details Get a Quote |
| BV-2-Cas9 | EDC01598 | Mouse | 5315 | Details Get a Quote |
| Kupffer-Cas9 | EDC01560 | Mouse | 5315 | Details Get a Quote |
| MB49-Cas9 | EDC01514 | Mouse | 5315 | Details Get a Quote |
| SLC2A1 Knockout HCT 116 Cell Line | EDJ-KQ21119 | Human | 6513 | Details Get a Quote |
| SLC2A1 Knockout HeLa Cell Line | EDJ-KQ21120 | Human | 6513 | Details Get a Quote |
| HK2 Knockout HCT 116 Cell Line | EDJ-KQ21127 | Human | 3099 | Details Get a Quote |
| HK2 Knockout HeLa Cell Line | EDJ-KQ21128 | Human | 3099 | Details Get a Quote |
| SLC2A4 Knockout HCT 116 Cell Line | EDJ-KQ21167 | Human | 6517 | Details Get a Quote |
| SLC2A3 Knockout A-549 Cell Line | EDJ-KQ26121 | Human | 6515 | Details Get a Quote |
| SLC2A3 Knockout HCT 116 Cell Line | EDJ-KQ26122 | Human | 6515 | Details Get a Quote |
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