Neuroscience
Neuroscience seeks to understand the complex mechanisms underlying nervous system development, function, and disease. Processes such as neuronal signaling, synaptic plasticity, neuronal survival, and neuroinflammation are regulated by intricate signaling networks, including neurotrophic factor pathways, neurotransmitter receptor signaling, and immune-inflammatory pathways. Together, these pathways maintain nervous system homeostasis and adaptability.
Disruptions in these pathways can contribute to neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, neurodevelopmental disorders including autism spectrum disorder, and impaired recovery following neural injury. Understanding the molecular basis of these processes is critical for uncovering disease mechanisms and developing new therapeutic strategies.
EDITGENE offers a collection of neuroscience-related knockout cell lines, covering pathways involved in neurotrophic signaling, neurotransmitter receptors, synaptic plasticity, and neuroinflammation. These validated models support research in neural development, neurodegenerative diseases, and neuroprotection.
We also provide ready-to-use and custom knockout cell lines to support diverse neuroscience research needs, with additional pathway models continuously being added.
