Overview
Apoptosis (Cancer)
Study programmed cell death pathways, apoptosis regulation and cancer cell survival mechanisms using CRISPR-engineered cell models.
What is Apoptosis (Cancer) ?
Apoptosis is a programmed cell death process that maintains tissue homeostasis and eliminates damaged cells. Cancer cells often develop mechanisms to evade apoptosis, allowing uncontrolled growth and survival. Understanding apoptosis regulation provides critical insights into cancer biology and supports the development of targeted therapies that restore cancer cell death.
Key Research Applications
Apoptosis pathway studies
Cancer cell survival mechanism research
Pro-apoptotic drug screening
Targeted therapy development
Cell death mechanism analysis
Products
Featured/Popular Targets
ALL
CASP2
CASP3
CASP6
CASP7
CASP8
CASP9
FADD
BCL2L2
BIRC2
MLKL
RIPK1
RIPK2
TNFRSF1A
TNFRSF1B
TRAF2
TRAF3
TRAF5
APAF1
AIFM2
CYLD
OPTN
SQSTM1
Product name Cat.No. Species Gene ID
RIPK1 Knockout NCTC clone 929 Cell Line EDJ-KQ50 Mouse 8737 Details Get a Quote
TNFRSF1A Knockout HEK293 Cell Line EDC90705 Human 7132 Details Get a Quote
CASP9 Knockout HEK293 Cell Line EDJ-KQ183 Human 842 Details Get a Quote
SQSTM1 Knockout HEK293 Cell Line EDC08337 Human 8878 Details Get a Quote
OPTN Knockout HEK293T Cell Line EDJ-KQ197 Human 10133 Details Get a Quote
BIRC2 Knockout HEK293 Cell Line EDJ-KQ543 Human 329 Details Get a Quote
CYLD Knockout HEK293 Cell Line EDJ-KQ560 Human 1540 Details Get a Quote
TRAF2 Knockout HEK293 Cell Line EDJ-KQ601 Human 7186 Details Get a Quote
TRAF3 Knockout HEK293 Cell Line EDJ-KQ602 Human 7187 Details Get a Quote
TRAF5 Knockout HEK293 Cell Line EDJ-KQ603 Human 7188 Details Get a Quote
CASP3 Knockout HEK293 Cell Line EDJ-KQ632 Human 836 Details Get a Quote
TNFRSF1B Knockout HEK293 Cell Line EDJ-KQ900 Human 7133 Details Get a Quote
MLKL Knockout HEK293 Cell Line EDJ-KQ1471 Human 197259 Details Get a Quote
FADD Knockout HEK293 Cell Line EDJ-KQ1473 Human 8772 Details Get a Quote
CASP8 Knockout HEK293 Cell Line EDJ-KQ1474 Human 841 Details Get a Quote
Displaying Records 1 To 15 Of 124 Records
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