Overview
Hypertension
Study blood pressure regulation, vascular tone, renal sodium handling and hypertensive signaling pathways using CRISPR-engineered cell and animal models.
What is Hypertension ?
Hypertension is a chronic medical condition of persistently elevated arterial pressure, driven by complex interactions among vascular, renal, neural and endocrine systems. Key mechanisms include renin-angiotensin-aldosterone system activation, endothelial dysfunction and altered ion transport. CRISPR models help dissect genetic contributions and identify novel antihypertensive drug targets.
Key Research Applications
RAAS component knockout studies
Endothelial NO signaling assays
Renal sodium transporter profiling
Antihypertensive target validation
Blood pressure GWAS gene function analysis
Products
Featured/Popular Targets
ALL
ACE
AGT
ADRB1
ADRB2
ADRA1A
SCNN1D
NOS3
EDN1
SLC12A1
SLC12A2
Product name Cat.No. Species Gene ID
NOS3 Knockout HEK293 Cell Line EDJ-KQ840 Human 4846 Details Get a Quote
EDN1 Knockout HEK293 Cell Line EDJ-KQ1485 Human 1906 Details Get a Quote
ADRB2 Knockout HEK293 Cell Line EDJ-KQ1553 Human 154 Details Get a Quote
ADRA1A Knockout HEK293 Cell Line EDJ-KQ1583 Human 148 Details Get a Quote
AGT Knockout HEK293 Cell Line EDJ-KQ1715 Human 183 Details Get a Quote
SCNN1D Knockout HEK293 Cell Line EDJ-KQ3283 Human 6339 Details Get a Quote
ACE Knockout HEK293 Cell Line EDJ-KQ4427 Human 1636 Details Get a Quote
SLC12A2 Knockout HEK293 Cell Line EDC90549 Human 6558 Details Get a Quote
SLC12A1 Knockout HEK293 Cell Line EDJ-KQ5795 Human 6557 Details Get a Quote
EDN1 Knockout A-549 Cell Line EDJ-KQ21075 Human 1906 Details Get a Quote
EDN1 Knockout HCT 116 Cell Line EDJ-KQ21076 Human 1906 Details Get a Quote
EDN1 Knockout HeLa Cell Line EDJ-KQ21077 Human 1906 Details Get a Quote
ACE Knockout HCT 116 Cell Line EDJ-KQ26969 Human 1636 Details Get a Quote
SLC12A2 Knockout A-549 Cell Line EDJ-KQ29200 Human 6558 Details Get a Quote
SLC12A2 Knockout HCT 116 Cell Line EDJ-KQ29201 Human 6558 Details Get a Quote
Displaying Records 1 To 15 Of 42 Records
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