Overview
Cardiac Development & Function
Study heart morphogenesis, cardiomyocyte differentiation, cardiac gene regulation and congenital heart disease mechanisms using CRISPR-engineered cell and organoid models.
What is Cardiac Development & Function ?
Cardiac development is a precisely orchestrated process involving progenitor cell specification, heart tube formation, chamber morphogenesis and valve formation. Transcription factor networks and signaling pathways (e.g., BMP, Wnt) coordinate these events. Disruptions lead to congenital heart defects, the most common birth anomaly.
Key Research Applications
Cardiomyocyte differentiation from iPSCs
Transcription factor network mapping
Congenital heart disease gene validation
Cardiac organoid development
Developmental toxicity screening
Products
Featured/Popular Targets
ALL
GATA4
GATA2
MYLK
MYLK3
GATA3
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| MYLK Knockout Caco-2 Cell Line | EDJ-KQ11 | Human | 4638 | Details Get a Quote |
| MYLK3 Knockout HEK293 Cell Line | EDJ-KQ853 | Human | 91807 | Details Get a Quote |
| GATA3 Knockout HEK293 Cell Line | EDJ-KQ1017 | Human | 2625 | Details Get a Quote |
| MYLK Knockout HEK293 Cell Line | EDJ-KQ1434 | Human | 4638 | Details Get a Quote |
| GATA4 Knockout HEK293 Cell Line | EDJ-KQ1836 | Human | 2626 | Details Get a Quote |
| GATA2 Knockout HEK293 Cell Line | EDJ-KQ4687 | Human | 2624 | Details Get a Quote |
| GATA3 Knockout A-549 Cell Line | EDJ-KQ20091 | Human | 2625 | Details Get a Quote |
| GATA3 Knockout HCT 116 Cell Line | EDJ-KQ20092 | Human | 2625 | Details Get a Quote |
| MYLK Knockout A-549 Cell Line | EDJ-KQ20978 | Human | 4638 | Details Get a Quote |
| MYLK Knockout HCT 116 Cell Line | EDJ-KQ20979 | Human | 4638 | Details Get a Quote |
| MYLK Knockout HeLa Cell Line | EDJ-KQ20980 | Human | 4638 | Details Get a Quote |
| MYLK3 Knockout HeLa Cell Line | EDJ-KQ20983 | Human | 91807 | Details Get a Quote |
| GATA4 Knockout A-549 Cell Line | EDJ-KQ21691 | Human | 2626 | Details Get a Quote |
| GATA2 Knockout A-549 Cell Line | EDJ-KQ27390 | Human | 2624 | Details Get a Quote |
| GATA2 Knockout HCT 116 Cell Line | EDJ-KQ27391 | Human | 2624 | Details Get a Quote |
Displaying Records 1 To 15 Of 30 Records
