Overview
Cell Differentiation
Study lineage commitment, differentiation signaling and cell type specification mechanisms using CRISPR-engineered cell and organoid models.
What is Cell Differentiation ?
Cell differentiation is the process by which stem or progenitor cells acquire specialized functions and morphology through regulated gene expression changes. Key signaling pathways (e.g., Notch, BMP, FGF) and transcription factors direct lineage decisions. Understanding differentiation is fundamental to developmental biology, regenerative medicine and cancer stem cell research.
Key Research Applications
Directed differentiation protocols
Lineage reporter cell line generation
Transcription factor function studies
Stem cell therapy target discovery
Products
Featured/Popular Targets
ALL
PAX6
FOXA1
FOXA2
FOXG1
GATA2
GATA3
SPI1
PPARG
SMAD1
SMAD3
SMAD4
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| SMAD1 Knockout HEK293 Cell Line | EDJ-KQ399 | Human | 4086 | Details Get a Quote |
| SMAD3 Knockout HEK293 Cell Line | EDJ-KQ400 | Human | 4088 | Details Get a Quote |
| SMAD4 Knockout HEK293 Cell Line | EDJ-KQ401 | Human | 4089 | Details Get a Quote |
| GATA3 Knockout HEK293 Cell Line | EDJ-KQ1017 | Human | 2625 | Details Get a Quote |
| PPARG Knockout HEK293 Cell Line | EDJ-KQ1115 | Human | 5468 | Details Get a Quote |
| FOXA1 Knockout HEK293 Cell Line | EDJ-KQ2840 | Human | 3169 | Details Get a Quote |
| FOXA2 Knockout HEK293 Cell Line | EDJ-KQ2898 | Human | 3170 | Details Get a Quote |
| SPI1 Knockout HEK293 Cell Line | EDJ-KQ3280 | Human | 6688 | Details Get a Quote |
| GATA2 Knockout HEK293 Cell Line | EDJ-KQ4687 | Human | 2624 | Details Get a Quote |
| PAX6 Knockout HEK293 Cell Line | EDJ-KQ5409 | Human | 5080 | Details Get a Quote |
| SMAD3 Knockout HeLa Cell Line | EDJ-KQ17985 | Human | 4088 | Details Get a Quote |
| GATA3 Knockout A-549 Cell Line | EDJ-KQ20091 | Human | 2625 | Details Get a Quote |
| GATA3 Knockout HCT 116 Cell Line | EDJ-KQ20092 | Human | 2625 | Details Get a Quote |
| SMAD1 Knockout A-549 Cell Line | EDJ-KQ18634 | Human | 4086 | Details Get a Quote |
| SMAD1 Knockout HCT 116 Cell Line | EDJ-KQ18635 | Human | 4086 | Details Get a Quote |
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