Gene Expression & Regulation
Gene expression and regulation are fundamental to cellular biology, encompassing processes such as transcriptional regulation, epigenetic modification, RNA processing, and translational control. Dysregulation of these mechanisms is closely associated with developmental disorders, cancer, metabolic diseases, and neurodegenerative conditions. Systematic investigation of gene regulatory networks requires reliable and well-characterized gene knockout models.
EDITGENE offers a collection of gene expression and regulation knockout cell lines, covering pathways involved in positive regulation of pri-miRNA transcription, epigenetic regulation, transcription factor networks, RNA splicing, and mRNA stability. These validated models enable researchers to investigate the molecular mechanisms controlling gene expression and their roles in development, disease progression, and therapeutic response.
We also provide ready-to-use and custom knockout cell lines to support a wide range of gene regulation studies, with additional pathway models continuously being added.
