Overview
Wnt Signaling
Study WNT signal transduction, β-catenin regulation, stem cell renewal and cancer-associated WNT pathway mechanisms using CRISPR-engineered cell models.
What is Wnt Signaling ?
WNT signaling is a fundamental pathway that regulates embryonic development, tissue homeostasis and stem cell maintenance. Aberrant WNT pathway activation, often through mutations in APC or β-catenin, drives colorectal and other cancers. It is a major target for cancer stem cell therapies and regenerative medicine.
Key Research Applications
WNT/β-catenin pathway reporter assays
Cancer stem cell self-renewal studies
WNT inhibitor development
Tissue regeneration research
Colon cancer model analysis
Products
Featured/Popular Targets
ALL
WNT5A
CTNNB1
GSK3A
GSK3B
CSNK1D
CSNK1E
CSNK1G2
CSNK1G3
LRP5
LRP6
FZD5
Product name Cat.No. Species Gene ID
CTNNB1 Knockout HCT 116 Cell Line EDJ-KQ22 Human 1499 Details Get a Quote
LRP6 Knockout HEK293T Cell Line EDJ-KQ94 Human 4040 Details Get a Quote
CTNNB1 Knockout HEK293 Cell Line EDC07547 Human 1499 Details Get a Quote
FZD5 Knockout HEK293 Cell Line EDJ-KQ306 Human 7855 Details Get a Quote
LRP5 Knockout HEK293 Cell Line EDJ-KQ313 Human 4041 Details Get a Quote
LRP6 Knockout HEK293 Cell Line EDJ-KQ314 Human 4040 Details Get a Quote
WNT5A Knockout HEK293 Cell Line EDJ-KQ354 Human 7474 Details Get a Quote
CSNK1G2 Knockout HEK293 Cell Line EDJ-KQ887 Human 1455 Details Get a Quote
CSNK1G3 Knockout HEK293 Cell Line EDJ-KQ888 Human 1456 Details Get a Quote
GSK3B Knockout HEK293 Cell Line EDJ-KQ902 Human 2932 Details Get a Quote
CSNK1D Knockout HEK293 Cell Line EDJ-KQ1391 Human 1453 Details Get a Quote
GSK3A Knockout HEK293 Cell Line EDJ-KQ4806 Human 2931 Details Get a Quote
LRP5 Knockout HeLa Cell Line EDJ-KQ17954 Human 4041 Details Get a Quote
CTNNB1 Knockout A-549 Cell Line EDJ-KQ17963 Human 1499 Details Get a Quote
FZD5 Knockout HCT 116 Cell Line EDJ-KQ17967 Human 7855 Details Get a Quote
Displaying Records 1 To 15 Of 56 Records
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