Overview
Bacterial Infection
Study host–pathogen interactions, bacterial entry and replication, immune evasion and infection mechanisms using CRISPR-engineered host cell and bacterial models.
What is Bacterial Infection ?
Bacterial infection involves the invasion and colonization of host tissues by pathogenic bacteria, which employ virulence factors, secretion systems and toxins to subvert host defenses. Host cells respond with innate immune and stress pathways. Understanding these interactions enables the development of anti-infective drugs, vaccines and host-directed therapies.
Key Research Applications
Host entry factor identification
Intracellular replication assays
Virulence factor screening
Inflammasome/cell death pathway studies
Antibiotic potentiation and resistance profiling
Products
Featured/Popular Targets
ALL
NOD2
TLR2
TLR4
TLR9
GSDMD
IRF5
IRF7
NFKB2
RELA
CYBB
NOS2
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| NFKB2 Knockout HEK293 Cell Line | EDJ-KQ579 | Human | 4791 | Details Get a Quote |
| RELA Knockout HEK293 Cell Line | EDJ-KQ588 | Human | 5970 | Details Get a Quote |
| IRF7 Knockout HEK293 Cell Line | EDJ-KQ993 | Human | 3665 | Details Get a Quote |
| NOS2 Knockout HEK293 Cell Line | EDJ-KQ1428 | Human | 4843 | Details Get a Quote |
| NOD2 Knockout HEK293 Cell Line | EDJ-KQ1486 | Human | 64127 | Details Get a Quote |
| TLR4 Knockout HEK293 Cell Line | EDJ-KQ1491 | Human | 7099 | Details Get a Quote |
| IRF5 Knockout HEK293 Cell Line | EDJ-KQ3840 | Human | 3663 | Details Get a Quote |
| GSDMD Knockout HEK293 Cell Line | EDJ-KQ12933 | Human | 79792 | Details Get a Quote |
| CYBB Knockout HEK293 Cell Line | EDJ-KQ17866 | Human | 1536 | Details Get a Quote |
| TLR2 Knockout HEK293 Cell Line | EDJ-KQ17909 | Human | 7097 | Details Get a Quote |
| TLR2 Knockout A-549 Cell Line | EDC90495 | Human | 7097 | Details Get a Quote |
| NFKB2 Knockout A-549 Cell Line | EDJ-KQ18988 | Human | 4791 | Details Get a Quote |
| NFKB2 Knockout HCT 116 Cell Line | EDJ-KQ18989 | Human | 4791 | Details Get a Quote |
| NFKB2 Knockout HeLa Cell Line | EDJ-KQ18990 | Human | 4791 | Details Get a Quote |
| RELA Knockout A-549 Cell Line | EDJ-KQ19008 | Human | 5970 | Details Get a Quote |
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