Overview
NK Cell Signaling
Study natural killer cell receptor signaling, activation, cytotoxicity and immune surveillance using CRISPR-engineered NK cell models.
What is NK Cell Signaling ?
NK cells are innate lymphocytes that kill virus-infected and tumor cells without prior sensitization. Their activity is governed by a balance of activating (e.g., NKG2D, CD16) and inhibitory (e.g., KIR, NKG2A) receptors. CRISPR-engineered NK cells are being developed for enhanced cancer immunotherapy.
Key Research Applications
NK cell cytotoxicity assays
Activating/inhibitory receptor pathway analysis
ADCC functional enhancement
CAR-NK cell target validation
Missing-self recognition studies
Products
Featured/Popular Targets
ALL
KLRK1
SYK
LYN
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| LYN Knockout HEK293 Cell Line | EDJ-KQ574 | Human | 4067 | Details Get a Quote |
| SYK Knockout HEK293 Cell Line | EDJ-KQ590 | Human | 6850 | Details Get a Quote |
| KLRK1 Knockout HEK293 Cell Line | EDJ-KQ17729 | Human | 22914 | Details Get a Quote |
| LYN Knockout HeLa Cell Line | EDJ-KQ18031 | Human | 4067 | Details Get a Quote |
| LYN Knockout A-549 Cell Line | EDJ-KQ18970 | Human | 4067 | Details Get a Quote |
| LYN Knockout HCT 116 Cell Line | EDJ-KQ18971 | Human | 4067 | Details Get a Quote |
| SYK Knockout HCT 116 Cell Line | EDJ-KQ19018 | Human | 6850 | Details Get a Quote |
| KLRK1 Knockout HCT 116 Cell Line | EDJ-KQ19804 | Human | 22914 | Details Get a Quote |
| SYK Knockout HeLa Cell Line | EDJ-KQ54597 | Human | 6850 | Details Get a Quote |
| KLRK1 Knockout HeLa Cell Line | EDJ-KQ55654 | Human | 22914 | Details Get a Quote |
| SYK Knockout A-549 Cell Line | EDJ-KQ63079 | Human | 6850 | Details Get a Quote |
| KLRK1 Knockout A-549 Cell Line | EDJ-KQ64153 | Human | 22914 | Details Get a Quote |
| LYN Knockout HAP1 Cell Line | EDC07799 | Human | 4067 | Details Get a Quote |
| KLRK1 Overexpression HEK293 Stable Cell Line | EDJ-GQ122 | Human | 22914 | Details Get a Quote |
Displaying Records 1 To 14 Of 14 Records
