Overview
Cytokines & Chemokines
Study cytokine and chemokine expression, release and signaling networks in immune regulation, inflammation and tumor microenvironment using CRISPR-engineered cell models.
What is Cytokines & Chemokines ?
Cytokines and chemokines are small secreted proteins that mediate intercellular communication in immune responses, directing cell activation, migration and differentiation. They are key players in inflammation, autoimmune disease and cancer immune evasion. Targeting cytokine/chemokine axes has led to blockbuster therapies like TNF inhibitors and IL-6 receptor antagonists.
Key Research Applications
Cytokine/chemokine multiplex profiling
Chemotaxis and migration assays
Tumor microenvironment modeling
Anti-cytokine therapy screening
Immune cell polarization studies
Products
Featured/Popular Targets
ALL
IL1B
IL6
IL10
IL4I1
IL7R
IL11RA
IL1RL1
CSF2
TNF
IFNG
TGFB1
TGFB2
Product name Cat.No. Species Gene ID
IFNg Overexpression HEK293 Stable Cell Line EDJ-GQ88 Human 3458 Details Get a Quote
IL1B Knockout HEK293 Cell Line EDJ-KQ140 Human 3553 Details Get a Quote
CSF2 Knockout HEK293 Cell Line EDJ-KQ455 Human 1437 Details Get a Quote
IL6 Knockout HEK293 Cell Line EDJ-KQ498 Human 3569 Details Get a Quote
IL7R Knockout HEK293 Cell Line EDJ-KQ502 Human 3575 Details Get a Quote
IFNG Knockout HEK293 Cell Line EDJ-KQ1492 Human 3458 Details Get a Quote
IL4I1 Knockout HEK293 Cell Line EDJ-KQ3808 Human 259307 Details Get a Quote
IL1RL1 Knockout HEK293 Cell Line EDJ-KQ6485 Human 9173 Details Get a Quote
TNF Knockout HEK293 Cell Line EDJ-KQ17672 Human 7124 Details Get a Quote
TGFB1 Knockout HEK293 Cell Line EDJ-KQ17770 Human 7040 Details Get a Quote
TGFB2 Knockout HEK293 Cell Line EDJ-KQ17771 Human 7042 Details Get a Quote
IL1B Knockout HeLa Cell Line EDJ-KQ18960 Human 3553 Details Get a Quote
IL6 Knockout A-549 Cell Line EDJ-KQ18810 Human 3569 Details Get a Quote
IL6 Knockout HeLa Cell Line EDJ-KQ18811 Human 3569 Details Get a Quote
IL7R Knockout HeLa Cell Line EDC10330 Human 3575 Details Get a Quote
Displaying Records 1 To 15 Of 57 Records
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