Overview
Host-Pathogen Interaction
Study mechanisms of pathogen attachment, invasion, intracellular survival and host immune evasion using CRISPR-engineered host and pathogen models.
What is Host-Pathogen Interaction ?
Host–pathogen interactions encompass the molecular crosstalk that determines the outcome of infection. Pathogens deploy virulence factors, secretion systems and immune evasion strategies, while hosts mount innate and adaptive defenses. CRISPR screens identify host factors essential for pathogen entry and replication, offering new targets for host-directed therapies.
Key Research Applications
Genome-wide host factor screening
Intracellular pathogen growth assays
Immune evasion mechanism studies
Virulence effector target identification
Anti-infective host-directed target discovery
Products
Featured/Popular Targets
ALL
TLR2
TLR3
TLR4
TLR6
TLR7
TLR8
TLR9
NOD2
NLRC5
NLRX1
AIM2
CGAS
STING1
MYD88
TICAM1
IRF3
IRF5
IRF7
NFKB2
RELA
RIPK2
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| MYD88 Knockout HEK293 Cell Line | EDJ-KQ578 | Human | 4615 | Details Get a Quote |
| NFKB2 Knockout HEK293 Cell Line | EDJ-KQ579 | Human | 4791 | Details Get a Quote |
| RELA Knockout HEK293 Cell Line | EDJ-KQ588 | Human | 5970 | Details Get a Quote |
| TICAM1 Knockout HEK293 Cell Line | EDJ-KQ593 | Human | 148022 | Details Get a Quote |
| IRF3 Knockout HEK293 Cell Line | EDJ-KQ960 | Human | 3661 | Details Get a Quote |
| IRF7 Knockout HEK293 Cell Line | EDJ-KQ993 | Human | 3665 | Details Get a Quote |
| AIM2 Knockout HEK293 Cell Line | EDJ-KQ1059 | Human | 9447 | Details Get a Quote |
| NOD2 Knockout HEK293 Cell Line | EDJ-KQ1486 | Human | 64127 | Details Get a Quote |
| TLR4 Knockout HEK293 Cell Line | EDJ-KQ1491 | Human | 7099 | Details Get a Quote |
| TLR7 Knockout HEK293 Cell Line | EDJ-KQ2074 | Human | 51284 | Details Get a Quote |
| TLR8 Knockout HEK293 Cell Line | EDJ-KQ2816 | Human | 51311 | Details Get a Quote |
| IRF5 Knockout HEK293 Cell Line | EDJ-KQ3840 | Human | 3663 | Details Get a Quote |
| CGAS Knockout HEK293 Cell Line | EDJ-KQ3916 | Human | 115004 | Details Get a Quote |
| RIPK2 Knockout HEK293 Cell Line | EDJ-KQ6357 | Human | 8767 | Details Get a Quote |
| TLR6 Knockout HEK293 Cell Line | EDJ-KQ7010 | Human | 10333 | Details Get a Quote |
Displaying Records 1 To 15 Of 140 Records
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