Overview
Antigen Processing & Presentation
Study antigen processing, MHC class I/II presentation, peptide loading and immune recognition mechanisms using CRISPR-engineered cell models.
What is Antigen Processing & Presentation ?
Antigen processing and presentation is the process by which protein antigens are degraded into peptides, loaded onto major histocompatibility complex (MHC) molecules and presented on the cell surface for T cell recognition. This pathway is central to immune surveillance, vaccine development and cancer immunotherapy, where defects can enable immune escape.
Key Research Applications
MHC-I/II pathway component knockout studies
Neoantigen presentation assays
T cell recognition validation
Immunotherapy target discovery
Products
Featured/Popular Targets
ALL
B2M
HLA-E
PSMB8
PSMB9
PSMB10
CD74
| Product name | Cat.No. | Species | Gene ID | |
|---|---|---|---|---|
| B2M Knockout A-549 Cell Line | EDC07863 | Human | 567 | Details Get a Quote |
| B2M Knockout HEK293T Cell Line | EDC07693 | Human | 567 | Details Get a Quote |
| B2M Knockout Hep-G2 Cell Line | EDJ-KQ38 | Human | 567 | Details Get a Quote |
| B2M Knockout C2C12 Cell Line | EDJ-KQ82 | Mouse | 12010 | Details Get a Quote |
| B2M Knockout K-562 Cell Line | EDJ-KQ85 | Human | 567 | Details Get a Quote |
| B2M Knockout SNU-449 Cell Line | EDJ-KQ89 | Human | 567 | Details Get a Quote |
| B2M Knockout THP-1 Cell Line | EDJ-KQ91 | Human | 567 | Details Get a Quote |
| PSMB10 Knockout HEK293 Cell Line | EDJ-KQ1927 | Human | 5699 | Details Get a Quote |
| PSMB9 Knockout HEK293 Cell Line | EDJ-KQ5575 | Human | 5698 | Details Get a Quote |
| B2M Knockout HEK293 Cell Line | EDJ-KQ12503 | Human | 567 | Details Get a Quote |
| HLA-E Knockout HEK293 Cell Line | EDJ-KQ13757 | Human | 3133 | Details Get a Quote |
| CD74 Knockout HEK293 Cell Line | EDC08272 | Human | 972 | Details Get a Quote |
| B2M Knockout HCT 116 Cell Line | EDJ-KQ41482 | Human | 567 | Details Get a Quote |
| B2M Knockout HeLa Cell Line | EDJ-KQ41483 | Human | 567 | Details Get a Quote |
| B2M Knockout A-375 Cell Line | EDC07626 | Human | 567 | Details Get a Quote |
Displaying Records 1 To 15 Of 36 Records
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