Overview
Atherosclerosis & Lipid
Study lipid metabolism, foam cell formation, vascular inflammation and atherosclerotic plaque development using CRISPR-engineered cell and animal models.
What is Atherosclerosis & Lipid ?
Atherosclerosis is a chronic inflammatory disease of the arterial wall characterized by lipid accumulation, immune cell infiltration and plaque formation. Dysregulated lipid metabolism, especially elevated LDL and defective reverse cholesterol transport, is central to its pathogenesis. Research aims to identify targets for plaque regression and cardiovascular event prevention.
Key Research Applications
Macrophage foam cell assays
Lipid uptake/efflux pathway studies
Endothelial dysfunction modeling
Vascular inflammation profiling
Anti-atherosclerosis target screening
Products
Featured/Popular Targets
ALL
LDLR
APOB
APOE
SCARB1
ABCA1
ABCG1
SREBF1
SREBF2
LPL
LIPA
SELP
MMP2
Product name Cat.No. Species Gene ID
APOE Knockout HEK293 Cell Line EDJ-KQ172 Human 348 Details Get a Quote
LDLR Knockout HEK293 Cell Line EDJ-KQ273 Human 3949 Details Get a Quote
SREBF2 Knockout HEK293 Cell Line EDJ-KQ1125 Human 6721 Details Get a Quote
SELP Knockout HEK293 Cell Line EDJ-KQ1371 Human 6403 Details Get a Quote
SREBF1 Knockout HEK293 Cell Line EDJ-KQ1869 Human 6720 Details Get a Quote
APOB Knockout HEK293 Cell Line EDJ-KQ2190 Human 338 Details Get a Quote
SCARB1 Knockout HEK293 Cell Line EDJ-KQ2450 Human 949 Details Get a Quote
ABCG1 Knockout HEK293 Cell Line EDJ-KQ3171 Human 9619 Details Get a Quote
LPL Knockout HEK293 Cell Line EDJ-KQ5140 Human 4023 Details Get a Quote
ABCA1 Knockout HEK293 Cell Line EDJ-KQ12244 Human 19 Details Get a Quote
MMP2 Knockout HEK293 Cell Line EDJ-KQ17782 Human 4313 Details Get a Quote
LIPA Knockout HEK293 Cell Line EDJ-KQ17862 Human 3988 Details Get a Quote
SCARB1 Knockout A-549 Cell Line EDJ-KQ22977 Human 949 Details Get a Quote
SCARB1 Knockout HCT 116 Cell Line EDJ-KQ22978 Human 949 Details Get a Quote
SCARB1 Knockout HeLa Cell Line EDJ-KQ22979 Human 949 Details Get a Quote
Displaying Records 1 To 15 Of 60 Records
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