TFE3 Knockout KGN Cell Line
Cat.No.:
EDJ-KQ48
Species:
Human
Cell Name:
KGN
Gene:
TFE3
Gene ID:
7030
Size:
1×10⁶cells
TFE3 Knockout Cell Line (KGN) is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performotion Cas9 Protein and Hassle-Free Cell Selection.
| Cat.No. | EDJ-KQ48 |
|---|---|
| Product Name | TFE3 Knockout Cell Line (KGN) |
| Cell line | KGN |
| Cellosaurus ID | CVCL_0375 |
| Gene | TFE3 |
| NCBI Gene ID | |
| Gene Synonyms | MRXSPF|RCCP2|RCCX1|TFEA|bHLHe33 |
| Summary |
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
|
| Morphology | Adherent |
| Passage Ratio | 1/3 2-3 days |
| Complete Culture Medium | DMEM/F-12+10%FBS |
| Freezing Medium | 90%Complete culture medium+10%DMSO |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: KGN | STR Info (Cell bank) Cell Line: KGN | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 12 | 10 | 12 |
| D5S818 | 13 | 13 | ||
| D7S820 | 11 | 11 | ||
| D13S317 | 9 | 9 | ||
| D16S539 | 10 | 12 | 10 | 12 |
| TH01 | 9 | 9 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 17 | 17 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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