TFE3 (NC_000023.11:g.49043201C>G) Point Mutation in A-549 Cell Line
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Cat.No.:
EDC03007
Species:
Human
Cell Name:
A-549
Gene:
TFE3
Gene ID:
7030
Size:
1×10⁶cells
The TFE3 (NC_000023.11:g.49043201C>G) Point Mutation in A549 Cell Line is based on the newly developed Bingo™ platform, which utilizes an optimized and upgraded version of the Prime Editing (PE) gene point mutation system-currently the most efficient and safest technology available. This platform enables precise and efficient gene point mutation, resulting in a highly active and stable cell line.
| Cat.No. | EDC03007 |
|---|---|
| Product Name | TFE3 (NC_000023.11:g.49043201C>G) Point Mutation in A-549 Cell Line |
| Cell Line | A-549 |
| Gene ID | |
| Cellosaurus ID | CVCL_0023 |
| Mutation Site | NC_000023.11:g.49043201C>G |
| Cell Line Synonyms | A 549, A549, NCI-A549, A549/ATCC, A549 ATCC, A549ATCC, hA549 |
| Summary |
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
|
| Associated Diseases | Non-Small Cell Lung Carcinoma |
| Passage Ratio | 1:4~1:5 |
| Complete Culture Medium | F-12K+10%FBS |
| Freezing Medium | 95% complete culture medium+5% DMSO |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: A-549 | STR Info (Cell bank) Cell Line: A-549 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1PO | 10 | 12 | 10 | 12 |
| D2S1338 | 24 | 24 | ||
| D3S1358 | 16 | 16 | ||
| D5S818 | 11 | 11 | ||
| D7S820 | 8 | 11 | 8 | 11 |
| D8S1179 | 13 | 14 | 13 | 14 |
| D13S317 | 11 | 11 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 14 | 17 | 14 | 17 |
| D19S433 | 13 | 13 | ||
| D21S11 | 29 | 29 | ||
| FGA | 23 | 23 | ||
| Penta D | 9 | 9 | ||
| Penta E | 7 | 11 | 7 | 11 |
| TH01 | 8 | 9.3 | 8 | 9.3 |
| TPOX | 8 | 11 | 8 | 11 |
| vWA | 14 | 14 | ||
| D6S1043 | 11 | 13 | ||
| D12S391 | 18 | 18 | ||
| D2S441 | 10 | 13 | 10 | 13 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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