Tsc2 Knockout NIH 3T3 Cell Line
Cat.No.:
EDJ-KZ66
Species:
Mouse
Cell Name:
NIH 3T3
Gene:
Tsc2
Gene ID:
22084
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ66 |
|---|---|
| Product Name | Tsc2 Knockout NIH/3T3 Cell Line |
| Cell Line | NIH 3T3 |
| Cellosaurus ID | CVCL_0594 |
| Cell Line Synonyms | NIH/3T3, NIH-3T3, NIH3T3, 3T3, 3T3NIH, 3T3-Swiss, Swiss-3T3, Swiss/3T3, Swiss 3T3, Swiss3T3 |
| Gene | Tsc2 |
| NCBI Gene ID | |
| Gene Synonyms | LAM|PPP1R160|TSC4 |
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: NIH 3T3 | STR Info (Cell bank) Cell Line: NIH 3T3 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| 1-1 | 10 | 10 | ||
| 1-2 | 13 | 17 | 13 | 17 |
| 2-1 | 9 | 9 | ||
| 3-2 | 14 | 15 | 14 | 15 |
| 4-2 | 19.3 | 20.3 | 19.3 | 20.3 |
| 5-5 | 14 | 15 | 14 | 15 |
| 6-4 | 16 | 15.3 | ||
| 6-7 | 12 | 12 | ||
| 7-1 | 29 | 29 | ||
| 8-1 | 15 | 15 | ||
| 11-2 | 15 | 17 | 15 | 17 |
| 12-1 | 20 | 20 | ||
| 13-1 | 16.2 | 16.2 | ||
| 15-3 | 20.3 | 20.3 | ||
| 17-2 | 13 | 14 | 13 | 14 |
| 18-3 | 17 | 19 | 17 | 19 |
| 19-2 | 11 | 12 | 11 | 12 |
| X-1 | 25 | 25 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Related Publications
Construction of TSC2 knockout cell line using CRISPR/Cas9 system and demonstration of its effects on NIH-3T3 cells.
IF=2.5
Cell biochemistry and biophysics
This KO model may be useful for:
- Studying mTOR signaling pathway regulation and cellular growth control
- Investigating the role of TSC2 in tumor suppression and cell proliferation
- Evaluating drug responses in TSC2-deficient cellular contexts
- Exploring mechanisms of autophagy and metabolic reprogramming
- Functional validation of CRISPR/Cas9-mediated gene editing in mammalian cells
Recommended Accessories
Cell Culture Optimization Series
Related Products
CRISPR Knockout Kit
Flash CRISPR Knockout Kit（Universal Version）Flash CRISPR Knockout Kit（Universal Version）
Flash-Pro CRISPR KO Kit (For Organoids / Stem Cells)Flash-Pro CRISPR KO Kit (For Organoids / Stem Cells)
