TSC2 Knockout U-87MG ATCC Cell Line
Cat.No.:
EDJ-KZ68
Species:
Human
Cell Name:
U-87MG ATCC
Gene:
TSC2
Gene ID:
7249
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ68 |
|---|---|
| Product Name | TSC2 Knockout U-87 MG Cell Line |
| Cell Line | U-87MG ATCC |
| Cellosaurus ID | CVCL_0022 |
| Cell Line Synonyms | U-87MG, U-87 MG, U87 MG, U-87-MG, U87-MG, U87MG, U-87, U87, 87 MG, 87MG |
| Gene | TSC2 |
| NCBI Gene ID | |
| Gene Synonyms | LAM|PPP1R160|TSC4 |
| Summary |
This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis. [provided by RefSeq, May 2022]
|
| Associated Diseases | Glioblastoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: U-87MG ATCC | STR Info (Cell bank) Cell Line: U-87MG ATCC | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 11 | 10 | 11 |
| D2S1338 | 20 | 23 | 20 | 23 |
| D3S1358 | 16 | 17 | 16 | 17 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 8 | 9 | 8 | 9 |
| D8S1179 | 10 | 11 | 10 | 11 |
| D13S317 | 8 | 11 | 8 | 11 |
| D16S539 | 12 | 12 | ||
| D18S51 | 13 | 13 | ||
| D19S433 | 15 | 15.2 | 15 | 15.2 |
| D21S11 | 28 | 32.2 | 28 | 32.2 |
| FGA | 18 | 24 | 18 | 24 |
| Penta D | 9 | 14 | 9 | 14 |
| Penta E | 7 | 14 | 7 | 14 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 8 | ||
| vWA | 15 | 17 | 15 | 17 |
| D6S1043 | 11 | 18 | ||
| D12S391 | 18 | 21 | 18 | 21 |
| D2S441 | 10 | 11 | 10 | 11 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Recommended Accessories
Cell Culture Optimization Series
Related Products
CRISPR Knockout Kit
Flash CRISPR Knockout Kit（Universal Version）Flash CRISPR Knockout Kit（Universal Version）
Flash-Pro CRISPR KO Kit (For Organoids / Stem Cells)Flash-Pro CRISPR KO Kit (For Organoids / Stem Cells)
