STING1 Knockout VeroE6/TMPRSS2 Cell Line
Cat.No.:
EDJ-KZ498
Species:
African green monkey
Cell Name:
VeroE6/TMPRSS2
Gene:
STING1
Gene ID:
340061
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ498 |
|---|---|
| Product Name | STING1 Knockout Vero E6 Cell Line |
| Species | African green monkey |
| Cell Line | VeroE6/TMPRSS2 |
| Cellosaurus ID | CVCL_YQ49 |
| Gene | |
| Gene Synonyms | ERIS|MITA|MPYS|NET23|SAVI|STING|STING-beta|TMEM173|hMITA|hSTING |
| Summary |
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.