STING1 Knockout VeroE6/TMPRSS2 Cell Line

STING1 Knockout VeroE6/TMPRSS2 Cell Line
Cat.No.:

EDJ-KZ498

Species:

African green monkey

Cell Name:

VeroE6/TMPRSS2

Gene:

STING1

Gene ID:

340061

Size:

1×10⁶cells

Cat.No. EDJ-KZ498
Product Name STING1 Knockout Vero E6 Cell Line
Species African green monkey
Cell Line VeroE6/TMPRSS2
Cellosaurus ID CVCL_YQ49
Gene
Gene Synonyms ERIS|MITA|MPYS|NET23|SAVI|STING|STING-beta|TMEM173|hMITA|hSTING
Summary
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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