STAT1 Knockout MDCK Cell Line
Cat.No.:
EDJ-KZ495
Species:
Dog
Cell Name:
MDCK
Gene:
STAT1
Gene ID:
6772
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ495 |
|---|---|
| Product Name | STAT1 Knockout MDCK Cell Line |
| Species | Dog |
| Cell Line | MDCK |
| Cellosaurus ID | CVCL_0422 |
| Gene | STAT1 |
| Gene Synonyms | CANDF7|IMD31A|IMD31B|IMD31C|ISGF-3|STAT91 |
| Summary |
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Required Companion Kits
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