Myd88 Knockout RAW 264.7 Cell Line
Cat.No.:
EDJ-KZ354
Species:
Mouse
Cell Name:
RAW 264.7
Gene:
Myd88
Gene ID:
17874
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ354 |
|---|---|
| Product Name | Myd88 Knockout RAW 264.7 Cell Line |
| Cell Line | RAW 264.7 |
| Cellosaurus ID | CVCL_0493 |
| Cell Line Synonyms | RAW264, RAW2647, RAW264.7, RAW-264.7, Raw 264.7, Raw264.7 |
| Gene | Myd88 |
| NCBI Gene ID | |
| Gene Synonyms | IMD68|MYD88D|WM1 |
| Associated Diseases | Leukemia |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: RAW 264.7 | STR Info (Cell bank) Cell Line: RAW 264.7 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| 1-1 | 16 | 15 | 16 | |
| 1-2 | 17 | 17 | ||
| 2-1 | 16 | 16 | ||
| 3-2 | 14 | 14 | ||
| 4-2 | 22.3 | 22.3 | ||
| 5-5 | 14 | 15 | 14 | |
| 6-4 | 17 | 18 | 18 | |
| 6-7 | 12 | 13 | 12 | |
| 7-1 | 25.2 | 25.2 | ||
| 8-1 | 13 | 13 | ||
| 11-2 | 17 | 17 | ||
| 12-1 | 16 | 16 | ||
| 13-1 | 16.2 | 16.2 | ||
| 15-3 | 22.3 | 22.3 | ||
| 17-2 | 14 | 16 | 14 | 16 |
| 18-3 | 18 | 18 | ||
| 19-2 | 14 | 14 | ||
| X-1 | 24 | 24 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Related Publications
Qing-Xue-Xiao-Zhi formula attenuates atherosclerosis by inhibiting macrophage lipid accumulation and inflammatory response via TLR4/MyD88/NF-κB pathway regulation.
IF=8.3
Phytomedicine : international journal of phytotherapy and phytopharmacology
Syk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages.
IF=5.9
Frontiers in immunology
Polysaccharide CPP-3a Promotes M1 Polarization of Macrophages via TLR4/2-MyD88-NF-κB/p38 MAPK Signaling Pathways.
IF=5.4
Marine drugs
Toxoplasma gondii microneme protein MIC3 induces macrophage TNF-α production and Ly6C expression via TLR11/MyD88 pathway.
IF=3.4
PLoS neglected tropical diseases
This KO model may be useful for:
- Investigating TLR/MyD88-dependent signaling pathways (e.g., TLR4/2, TLR11) in macrophage polarization and inflammatory responses.
- Studying the role of MyD88 in cytokine production (e.g., TNF-α) and surface marker expression (e.g., Ly6C, M1 polarization).
- Evaluating the impact of MyD88 deficiency on macrophage-mediated lipid accumulation and inflammatory regulation in atherosclerosis models.
- Functional validation of upstream regulators such as Syk kinase in MyD88-dependent inflammatory cascades.
- Drug screening and mechanistic studies of natural compounds or pathogens targeting the MyD88-NF-κB/p38 MAPK axis.
Required Accessories
Cell Culture Optimization Series
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