LIPA Knockout SH-SY5Y Cell Line

LIPA Knockout SH-SY5Y Cell Line
Cat.No.:

EDJ-KZ335

Species:

Human

Cell Name:

SH-SY5Y

Gene:

LIPA

Gene ID:

3988

Size:

1×10⁶cells

Cat.No. EDJ-KZ335
Product Name LIPA Knockout SH-SY5Y Cell Line
Cell Line SH-SY5Y
Cellosaurus ID CVCL_0019
Cell Line Synonyms SH-Sy5y, SHSY5Y, SHSY-5Y, SK-SH-SY5Y, SY5Y, SH-SY5Y Parental
Gene LIPA
NCBI Gene ID
Gene Synonyms CESD|LAL
Summary
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
Associated Diseases Neuroblastoma
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: SH-SY5Y
STR Info (Cell bank)
Cell Line: SH-SY5Y
Allele1Allele2Allele1Allele2
Amelogenin X X
CSF1PO 11 11
D5S818 12 12
D7S820 7 10 7 10
D13S317 11 11
D16S539 8 13 8 13
TPOX 8 11 8 11
vWA 14 18 14 18
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

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