IL4I1 Knockout MDA-MB-231 Cell Line
Cat.No.:
EDJ-KZ299
Species:
Human
Cell Name:
MDA-MB-231
Gene:
IL4I1
Gene ID:
259307
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ299 |
|---|---|
| Product Name | IL4I1 Knockout MDA-MB-231 Cell Line |
| Cell Line | MDA-MB-231 |
| Cellosaurus ID | CVCL_0062 |
| Cell Line Synonyms | MDA_MB_231, MDA-MB 231, MDA.MB.231, MDA MB 231, MDA MB231, MDA Mb231, MDA-MB231, MDAMB-231, MDAMB231, MDA-231, MDA-231P, MDA231, MDA231-BRE, MB231, MD Anderson-Metastatic Breast-231 |
| Gene | IL4I1 |
| Gene Synonyms | FIG1|LAAO|LAO|hIL4I1 |
| Summary |
This gene encodes a secreted L-amino acid oxidase protein which primarily catabolizes L-phenylalanine and, to a lesser extent, L-arginine. The expression of this gene is induced by the cytokine interleukin 4 in B cells. This gene is also expressed in macrophages and dendritic cells. This protein may play a role immune system escape as it is expressed in tumor-associated macrophages and suppresses T-cell responses. This protein also contains domains thought to be involved in the binding of flavin adenine dinucleotide (FAD) cofactor. Multiple transcript variants encoding different isoforms have been found for this gene. Some transcripts of this gene share a promoter and exons of the 5' UTR with the overlapping NUP62 gene. [provided by RefSeq, Jul 2020]
|
| Associated Diseases | Breast Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: MDA-MB-231 | STR Info (Cell bank) Cell Line: MDA-MB-231 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 12 | 13 | 12 | 13 |
| D5S818 | 12 | 12 | ||
| D7S820 | 8 | 9 | 8 | 9 |
| D13S317 | 13 | 13 | ||
| D16S539 | 12 | 12 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 15 | 18 | 15 | 18 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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