CXCR4 Knockout U2OS Cell Line
Cat.No.:
EDJ-KQ18082
Species:
Human
Cell Name:
U2OS
Gene:
CXCR4
Gene ID:
7852
Size:
1×10⁶cells
CXCR4 Knockout U-2 OS Cell Line is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performotion Cas9 Protein and Hassle-Free Cell Selection.
| Cat.No. | EDJ-KQ18082 |
|---|---|
| Product Name | CXCR4 Knockout U-2 OS Cell Line |
| Cell Line | U2OS |
| Cellosaurus ID | CVCL_0042 |
| Cell Line Synonyms | U-2 OS, U-2OS, U-2-OS, U2-OS, U20-S, U20S, 2T |
| Gene | CXCR4 |
| NCBI Gene ID | |
| Gene Synonyms | CD184|D2S201E|FB22|HM89|HSY3RR|LAP-3|LAP3|LCR1|LESTR|NPY3R|NPYR|NPYRL|NPYY3R|WHIM|WHIMS|WHIMS1 |
| Summary |
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Osteosarcoma |
| Morphology | Adherent |
| Passage Ratio | 1/3 2 days |
| Complete Culture Medium | mcCoy5A+10%FBS |
| Freezing Medium | 95%Complete culture medium+ 5% DMSO |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: U2OS | STR Info (Cell bank) Cell Line: U2OS | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 13 | 13 | ||
| D1S1656 | 15 | 17.3 | 16 | 17.3 |
| D2S1338 | 20 | 24 | 20 | 24 |
| D3S1358 | 16 | 16 | ||
| D5S818 | 11 | 11 | ||
| D6S1043 | 11 | 11 | ||
| D7S820 | 11 | 12 | 11 | 12 |
| D8S1179 | 12 | 14 | 12 | 14 |
| D12S391 | 19 | 20 | 19 | 20 |
| D13S317 | 13 | 13 | ||
| D16S539 | 11 | 12 | 11 | 12 |
| D18S51 | 14 | 14 | ||
| D19S433 | 15 | 15 | ||
| D21S11 | 31 | 31 | ||
| FGA | 20 | 20 | ||
| Penta D | 9 | 9 | ||
| Penta E | 10 | 13 | 10 | 13 |
| TH01 | 6 | 9.3 | 6 | 9.3 |
| TPOX | 11 | 12 | 11 | 12 |
| VWA | 14 | 18 | 14 | 18 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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