ATM Knockout 22Rv1 Cell Line
Cat.No.:
EDJ-KZ104
Species:
Human
Cell Name:
22Rv1
Gene:
ATM
Gene ID:
472
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ104 |
|---|---|
| Product Name | ATM Knockout 22Rv1 Cell Line |
| Cell Line | 22Rv1 |
| Cellosaurus ID | CVCL_1045 |
| Cell Line Synonyms | 22RV1, 22Rv-1, 22rV1, CWR-22rv1, CWR22-Rv1, CWR22R-V1, CWR22-R1, CWR22Rv1, CWR22R |
| Gene | ATM |
| Gene Synonyms | AT1|ATA|ATC|ATD|ATDC|ATE|TEL1|TELO1 |
| Summary |
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
|
| Associated Diseases | Prostate Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: 22Rv1 | STR Info (Cell bank) Cell Line: 22Rv1 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| Amelogenin | X | Y | X | Y | ||
| CSF1PO | 10 | 11 | 10 | 11 | ||
| D2S1338 | 17 | 18 | 17 | 18 | ||
| D3S1358 | 15 | 15 | ||||
| D5S818 | 11 | 13 | 11 | 13 | ||
| D7S820 | 9 | 10 | 11 | 9 | 10 | 11 |
| D8S1179 | 13 | 14 | 13 | 14 | ||
| D13S317 | 9 | 12 | 8 | 9 | 12 | |
| D16S539 | 12 | 12 | ||||
| D18S51 | 13 | 14 | 13 | 14 | ||
| D19S433 | 13 | 14 | 13 | 14 | ||
| D21S11 | 30 | 30 | ||||
| FGA | 19 | 23 | 19 | 23 | ||
| Penta D | 9 | 12 | 9 | 12 | ||
| Penta E | 5 | 13 | 5 | 13 | ||
| TH01 | 6 | 9.3 | 6 | 9.3 | ||
| TPOX | 8 | 8 | ||||
| vWA | 15 | 21 | 15 | 21 | ||
| D6S1043 | 16 | 16 | ||||
| D12S391 | 18 | 25 | 18 | 25 | ||
| D2S441 | 11 | 12 | 11 | 12 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Required Companion Kits
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