Spp1 Knockout 4T1 Cell Line
Cat.No.:
EDJ-KZ490
Species:
Mouse
Cell Name:
4T1
Gene:
Spp1
Gene ID:
20750
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ490 |
|---|---|
| Product Name | Spp1 Knockout 4T1 Cell Line |
| Cell Line | 4T1 |
| Cellosaurus ID | CVCL_0125 |
| Cell Line Synonyms | 4T1-A, 4T1.0, 4T1/WT |
| Gene | Spp1 |
| NCBI Gene ID | |
| Gene Synonyms | BNSP|BSPI|ETA-1|OPN |
| Associated Diseases | Breast cancer |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: 4T1 | STR Info (Cell bank) Cell Line: 4T1 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| 1-1 | 16 | 15 | 16 | |||
| 1-2 | 17 | 17 | ||||
| 2-1 | 16 | 17 | 16 | 17 | ||
| 3-2 | 14 | 15 | 14 | 15 | ||
| 4-2 | 21.3 | 21.3 | ||||
| 5-5 | 14 | 14 | ||||
| 6-4 | 18 | 18 | ||||
| 6-7 | 12 | 12 | ||||
| 7-1 | 25.2 | 25.2 | ||||
| 8-1 | 13 | 13 | ||||
| 11-2 | 18 | 19 | 18 | 19 | 20 | |
| 12-1 | 16 | 17 | 16 | |||
| 13-1 | 16.2 | 16.2 | ||||
| 15-3 | 22.3 | 22.3 | ||||
| 17-2 | 15 | 15 | ||||
| 18-3 | 18 | 19 | 18 | 19 | ||
| 19-2 | 13 | 13 | ||||
| X-1 | 24 | 25 | 25 | |||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Related Publications
MAL/SPP1 axis drives tumor proliferation and immune evasion via JAK2/STAT3 and MHC class Ib in breast cancer.
IF=4.7
International immunopharmacology
This KO model may be useful for:
- Investigating the role of SPP1 in tumor proliferation and immune evasion
- Studying the MAL/SPP1 axis in JAK2/STAT3 signaling pathway regulation
- Evaluating MHC class Ib-mediated immune modulation in breast cancer
- Functional validation of SPP1 as a target for cancer immunotherapy
- In vitro drug screening for agents targeting SPP1-driven oncogenic pathways
Required Accessories
Cell Culture Optimization Series
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