SOCS3 Knockout BEAS-2B Cell Line
Cat.No.:
EDJ-KZ487
Species:
Human
Cell Name:
BEAS-2B
Gene:
SOCS3
Gene ID:
9021
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ487 |
|---|---|
| Product Name | SOCS3 Knockout BEAS-2B Cell Line |
| Cell Line | BEAS-2B |
| Cellosaurus ID | CVCL_0168 |
| Cell Line Synonyms | Beas-2B, BEAS 2B, BEAS2B, Beas2B, Bronchial Epithelium transformed with Ad12-SV40 2B |
| Gene | SOCS3 |
| Gene Synonyms | ATOD4|CIS3|Cish3|SOCS-3|SSI-3|SSI3 |
| Summary |
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: BEAS-2B | STR Info (Cell bank) Cell Line: BEAS-2B | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| D5S818 | 12 | 13 | 12 | 13 |
| D13S317 | 13 | 13 | ||
| D7S820 | 10 | 13 | 10 | 13 |
| D16S539 | 12 | 12 | ||
| vWA | 17 | 18 | 17 | 18 |
| TH01 | 7 | 9.3 | 7 | 9.3 |
| TPOX | 6 | 11 | 6 | 11 |
| CSF1PO | 9 | 12 | 9 | 12 |
| D19S433 | 13.2 | 15.2 | 13.2 | 15.2 |
| D21S11 | 28 | 30 | 28 | 30 |
| D18S51 | 18 | 19 | 18 | 19 |
| D6S1043 | 12 | 18 | ||
| D3S1358 | 15 | 17 | 15 | 17 |
| Penta D | 2.2 | 13 | 2.2 | 13 |
| D2S441 | 11 | 11.3 | 11 | 11.3 |
| D8S1179 | 13 | 15 | 13 | 15 |
| Penta E | 5 | 8 | 5 | 8 |
| D12S391 | 17 | 18 | 17 | 18 |
| D2S1338 | 22 | 23 | 22 | 23 |
| FGA | 20 | 24 | 20 | 24 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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