SIRT3 Knockout HT-29 Cell Line
Product Details
| Cat.No. | EDJ-KZ461 | Product Name | SIRT3 Knockout HT-29 Cell Line |
|---|---|---|---|
| Cell Line | HT-29 | Cellosaurus ID | CVCL_0320 |
| Cell Line Synonyms | HT 29, HT29 | Gene | |
| NCBI Gene ID | Gene Synonyms | SIR2L3 | |
| Summary |
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]
|
Associated Diseases | Colorectal Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
STR Profile
| Loci | STR Info (Sample Cell) Sample Cell Line: HT-29 | STR Info (Cell bank) Cell Line: HT-29 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 11 | 12 | 11 | 12 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D13S317 | 11 | 12 | 11 | 12 |
| D16S539 | 11 | 12 | 11 | 12 |
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 17 | 19 | 17 | 19 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
