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PIM1 Knockout NCI-H1299 Cell Line
Cat.No.:
EDJ-KZ40
Species:
Human
Cell Name:
NCI-H1299
Gene:
PIM1
Gene ID:
5292
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ40 |
|---|---|
| Product Name | PIM1 Knockout NCI-H1299 Cell Line |
| Cell Line | NCI-H1299 |
| Cellosaurus ID | CVCL_0060 |
| Cell Line Synonyms | H1299, H-1299, NCIH1299 |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | PIM |
| Summary |
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
|
| Associated Diseases | Non-Small Cell Lung Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: NCI-H1299 | STR Info (Cell bank) Cell Line: NCI-H1299 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| Amelogenin | X | X | ||||
| CSF1PO | 12 | 12 | ||||
| D5S818 | 11 | 11 | ||||
| D7S820 | 10 | 10 | ||||
| D13S317 | 12 | 12 | ||||
| D16S539 | 12 | 13 | 12 | 13 | ||
| TPOX | 8 | 8 | ||||
| vWA | 16 | 17 | 18 | 16 | 17 | 18 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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