KLF4 Knockout IPEC-J2 Cell Line
Cat.No.:
EDJ-KZ311
Species:
Pig
Cell Name:
IPEC-J2
Gene:
KLF4
Gene ID:
9314
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ311 |
|---|---|
| Product Name | KLF4 Knockout IPEC-J2 Cell Line |
| Cell Line | IPEC-J2 |
| Cellosaurus ID | CVCL_2246 |
| Cell Line Synonyms | IPECJ2, Intestinal Porcine Epithelial Cell line-J2 |
| Gene |
KLF4
|
| Gene Synonyms | EZF|GKLF |
| Summary |
This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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