DRD2 Knockout MDA-MB-231 Cell Line
Cat.No.:
EDJ-KZ190
Species:
Human
Cell Name:
MDA-MB-231
Gene:
DRD2
Gene ID:
1813
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ190 |
|---|---|
| Product Name | DRD2 Knockout MDA-MB-231 Cell Line |
| Cell Line | MDA-MB-231 |
| Cellosaurus ID | CVCL_0062 |
| Cell Line Synonyms | MDA_MB_231, MDA-MB 231, MDA.MB.231, MDA MB 231, MDA MB231, MDA Mb231, MDA-MB231, MDAMB-231, MDAMB231, MDA-231, MDA-231P, MDA231, MDA231-BRE, MB231, MD Anderson-Metastatic Breast-231 |
| Gene | DRD2 |
| Gene Synonyms | D2DR|D2R |
| Summary |
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Breast Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: MDA-MB-231 | STR Info (Cell bank) Cell Line: MDA-MB-231 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 12 | 13 | 12 | 13 |
| D5S818 | 12 | 12 | ||
| D7S820 | 8 | 9 | 8 | 9 |
| D13S317 | 13 | 13 | ||
| D16S539 | 12 | 12 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 15 | 18 | 15 | 18 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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