SERPINE1 Knockout hCF Cell Line
Cat.No.:
EDJ-KQ19
Species:
Human
Cell Name:
hCF
Gene:
SERPINE1
Gene ID:
5054
Size:
1×10⁶cells
serpine1 Knockout Cell Line (HCF) is an exclusive upgraded CRISPR/Cas9 system-mediated gene knockout cell, with the advantages of Optimized Strategy Design, Efficient Cell Transfection, High-Performotion Cas9 Protein and Hassle-Free Cell Selection.
| Cat.No. | EDJ-KQ19 |
|---|---|
| Product Name | serpine1 Knockout Cell Line (HCF) |
| Species | Human |
| Cell line | HCF |
| Cellosaurus ID | CVCL_WD14 |
| Cell Line Synonyms | human Corneal Fibroblast |
| Gene | SERPINE1 |
| NCBI Gene ID | |
| Gene Synonyms | PAI|PAI-1|PAI1|PLANH1 |
| Summary |
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020]
|
| Morphology | Adherent |
| Passage Ratio | 1/10~1/8，3days |
| Complete Culture Medium | DMEM+10%FBS |
| Freezing Medium | 70% complete medium+20%FBS+10%DMSO |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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