SERPINE1 Knockout U-87MG ATCC Cell Line
Cat.No.:
EDJ-KZ449
Species:
Human
Cell Name:
U-87MG ATCC
Gene:
SERPINE1
Gene ID:
5054
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ449 |
|---|---|
| Product Name | SERPINE1 Knockout U-87 MG Cell Line |
| Cell Line | U-87MG ATCC |
| Cellosaurus ID | CVCL_0022 |
| Cell Line Synonyms | U-87MG, U-87 MG, U87 MG, U-87-MG, U87-MG, U87MG, U-87, U87, 87 MG, 87MG |
| Gene | SERPINE1 |
| Gene Synonyms | PAI|PAI-1|PAI1|PLANH1 |
| Summary |
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020]
|
| Associated Diseases | Glioblastoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: U-87MG ATCC | STR Info (Cell bank) Cell Line: U-87MG ATCC | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 11 | 10 | 11 |
| D2S1338 | 20 | 23 | 20 | 23 |
| D3S1358 | 16 | 17 | 16 | 17 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 8 | 9 | 8 | 9 |
| D8S1179 | 10 | 11 | 10 | 11 |
| D13S317 | 8 | 11 | 8 | 11 |
| D16S539 | 12 | 12 | ||
| D18S51 | 13 | 13 | ||
| D19S433 | 15 | 15.2 | 15 | 15.2 |
| D21S11 | 28 | 32.2 | 28 | 32.2 |
| FGA | 18 | 24 | 18 | 24 |
| Penta D | 9 | 14 | 9 | 14 |
| Penta E | 7 | 14 | 7 | 14 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 8 | ||
| vWA | 15 | 17 | 15 | 17 |
| D6S1043 | 11 | 18 | ||
| D12S391 | 18 | 21 | 18 | 21 |
| D2S441 | 10 | 11 | 10 | 11 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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