RNF213 Knockout hCMEC/D3 Cell Line
Cat.No.:
EDJ-KZ434
Species:
Human
Cell Name:
hCMEC/D3
Gene:
RNF213
Gene ID:
57674
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ434 |
|---|---|
| Product Name | RNF213 Knockout HCMEC/D3 Cell Line |
| Cell Line | HCMEC/D3 |
| Cellosaurus ID | CVCL_U985 |
| Cell Line Synonyms | HCMEC/D3, CMEC/D3, human Cortical Microvessels Endothelial Cells/D3 |
| Gene | |
| NCBI Gene ID | |
| Gene Synonyms | ALO17|C17orf27|KIAA1618|MYMY2|MYSTR|NET57 |
| Summary |
This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: hCMEC/D3 | STR Info (Cell bank) Cell Line: hCMEC/D3 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 10 | 12 | 10 | 12 |
| D1S1656 | 15.3 | 17.3 | 15.3 | 17.3 |
| D2S441 | 13 | 13 | ||
| D2S1338 | 16 | 20 | 16 | 20 |
| D3S1358 | 16 | 17 | 16 | 17 |
| D5S818 | 11 | 11 | ||
| D7S820 | 10 | 12 | 10 | 12 |
| D8S1179 | 15 | 16 | 15 | 16 |
| D10S1248 | 14 | 15 | 14 | 15 |
| D12S391 | 19.3 | 22 | 19.3 | 22 |
| D13S317 | 11 | 14 | 11 | 14 |
| D16S539 | 9 | 12 | 9 | 12 |
| D18S51 | 12 | 19 | 12 | 19 |
| D21S11 | 30 | 32.2 | 30 | 32.2 |
| D22S1045 | 11 | 15 | 11 | 15 |
| FGA | 22 | 26 | 22 | 26 |
| Penta D | 10 | 12 | 10 | 12 |
| Penta E | 5 | 10 | 5 | 10 |
| TH01 | 7 | 9 | 7 | 9 |
| TPOX | 10 | 11 | 10 | 11 |
| vWA | 14 | 17 | 14 | 17 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Recommended Accessories
Cell Culture Optimization Series
Related Products
CRISPR Knockout Kit
Flash CRISPR Knockout Kit（Universal Version）Flash CRISPR Knockout Kit（Universal Version）
Flash-Pro CRISPR KO Kit (For Organoids / Stem Cells)Flash-Pro CRISPR KO Kit (For Organoids / Stem Cells)
