GSR Knockout MDCK Cell Line
Cat.No.:
EDJ-KZ277
Species:
Dog
Cell Name:
MDCK
Gene:
GSR
Gene ID:
2936
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ277 |
|---|---|
| Product Name | GSR Knockout MDCK Cell Line |
| Species | Dog |
| Cell Line | MDCK |
| Cellosaurus ID | CVCL_0422 |
| Gene | GSR |
| Gene Synonyms | CNSHA10|GR|GSRD|HEL-75|HEL-S-122m |
| Summary |
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
|
| Associated Diseases | Non-tumor |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.