CPT1A Knockout Hep-G2 Cell Line
Cat.No.:
EDJ-KZ168
Species:
Human
Cell Name:
Hep-G2
Gene:
CPT1A
Gene ID:
1374
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ168 |
|---|---|
| Product Name | CPT1A Knockout Hep G2 Cell Line |
| Cell Line | Hep-G2 |
| Cellosaurus ID | CVCL_0027 |
| Cell Line Synonyms | HEP-G2, Hep G2, HEP G2, HepG2, HEPG2 |
| Gene | CPT1A |
| Gene Synonyms | CPT I|CPT1|CPT1-L|CPTI-L|L-CPT1 |
| Summary |
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
|
| Associated Diseases | Hepatocellular Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: Hep-G2 | STR Info (Cell bank) Cell Line: Hep-G2 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1P0 | 10 | 11 | 10 | 11 |
| D2S1338 | 19 | 20 | 19 | 20 |
| D3S1358 | 15 | 16 | 15 | 16 |
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D8S1179 | 15 | 16 | 15 | 16 |
| D13S317 | 9 | 13 | 9 | 13 |
| D16S539 | 12 | 12 | 13 | |
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 15.2 | 15.2 | ||
| D21S11 | 29 | 31 | 29 | 31 |
| FGA | 22 | 25 | 22 | 25 |
| Penta D | 9 | 13 | 9 | 13 |
| Penta E | 15 | 20 | 15 | 20 |
| TH01 | 9 | 9 | ||
| TPOX | 8 | 9 | 8 | 9 |
| vWA | 17 | 17 | ||
| D6S1043 | 13 | |||
| D12S391 | 21 | 25 | 21 | 25 |
| D2S441 | 11.3 | 14 | 11.3 | 14 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Cell Culture Optimization Series
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