CD276 Knockout MG-63 Cell Line
Cat.No.:
EDJ-KZ14
Species:
Human
Cell Name:
MG-63
Gene:
CD276
Gene ID:
80381
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ14 |
|---|---|
| Product Name | CD276 Knockout MG63 Cell Line |
| Cell Line | MG-63 |
| Cellosaurus ID | CVCL_0426 |
| Cell Line Synonyms | M-G63, MG63 |
| Gene | CD276 |
| Gene Synonyms | 4Ig-B7-H3|B7-H3|B7H3|B7RP-2 |
| Summary |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: MG-63 | STR Info (Cell bank) Cell Line: MG-63 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1PO | 10 | 12 | 10 | 12 |
| D2S1338 | 17 | 24 | 17 | 24 |
| D3S1358 | 15 | 15 | ||
| D5S818 | 11 | 12 | 11 | 12 |
| D7S820 | 10 | 10 | ||
| D8S1179 | 13 | 13 | ||
| D13S317 | 11 | 11 | ||
| D16S539 | 11 | 11 | ||
| D18S51 | 12 | 16 | 16 | |
| D19S433 | 13 | 14 | 13 | 14 |
| D21S11 | 30 | 30 | ||
| FGA | 21 | 25 | 21 | 25 |
| Penta D | 9 | 13 | 9 | 13 |
| Penta E | 11 | 12 | 11 | 12 |
| TH01 | 9.3 | 9.3 | ||
| TPOX | 8 | 11 | 8 | 11 |
| vWA | 16 | 19 | 16 | 19 |
| D6S1043 | 12 | 17 | ||
| D12S391 | 15 | 20 | ||
| D2S441 | 10 | 11 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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