ATG5 Knockout Huh-7 Cell Line
Cat.No.:
EDJ-KZ1
Species:
Human
Cell Name:
Huh-7
Gene:
ATG5
Gene ID:
9474
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ1 |
|---|---|
| Product Name | Atg5 Knockout HuH-7 Cell Line |
| Cell Line | Huh-7 |
| Cellosaurus ID | CVCL_0336 |
| Cell Line Synonyms | HuH-7, HUH-7, HuH7, Huh7, HUH7, HUH7.0, JTC-39, Japanese Tissue Culture-39 |
| Gene | Atg5 |
| Gene Synonyms | APG5|APG5-LIKE|APG5L|ASP|SCAR25|hAPG5 |
| Summary |
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
|
| Associated Diseases | Hepatocellular Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: Huh-7 | STR Info (Cell bank) Cell Line: Huh-7 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1P0 | 11 | 11 | ||
| D2S1338 | 19 | 19 | ||
| D3S1358 | 15 | 15 | ||
| D5S818 | 12 | 12 | ||
| D7S820 | 11 | 11 | ||
| D8S1179 | 14 | 14 | 15 | |
| D13S317 | 10 | 11 | 10 | 11 |
| D16S539 | 10 | 10 | ||
| D18S51 | 15 | 15 | ||
| D19S433 | 13 | 14 | 13 | 14 |
| D21S11 | 30 | 30 | ||
| FGA | 22 | 23 | 22 | 23 |
| Penta D | 12 | 12 | ||
| Penta E | 11 | 11 | ||
| TH01 | 7 | 7 | ||
| TPOX | 8 | 11 | 8 | 11 |
| vWA | 16 | 18 | 16 | 18 |
| D6S1043 | 13 | 15 | 13 | 15 |
| D12S391 | 20 | 21 | 20 | 21 |
| D2S441 | 12 | 14 | 12 | 14 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
Required Accessories
Required Companion Kits
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