ATG5 Knockout NCI-H1299 Cell Line

ATG5 Knockout NCI-H1299 Cell Line
Cat.No.:

EDJ-KZ10

Species:

Human

Cell Name:

NCI-H1299

Gene:

ATG5

Gene ID:

9474

Size:

1×10⁶cells

Cat.No. EDJ-KZ10
Product Name ATG5 Knockout NCI-H1299 Cell Line
Cell Line NCI-H1299
Cellosaurus ID CVCL_0060
Cell Line Synonyms H1299, H-1299, NCIH1299
Gene ATG5
Gene Synonyms APG5|APG5-LIKE|APG5L|ASP|SCAR25|hAPG5
Summary
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Associated Diseases Non-Small Cell Lung Carcinoma
QC Indels validated by Sanger sequencing; sterility confirmed via microbial testing.
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
LociSTR Info (Sample Cell)
Sample Cell Line: NCI-H1299
STR Info (Cell bank)
Cell Line: NCI-H1299
Allele1Allele2Allele3Allele1Allele2Allele3
Amelogenin X X
CSF1PO 12 12
D5S818 11 11
D7S820 10 10
D13S317 12 12
D16S539 12 13 12 13
TPOX 8 8
vWA 16 17 18 16 17 18
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.

Required Accessories

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