SENP7 Knockout SK-BR-3 Cell Line
Cat.No.:
EDJ-KZ448
Species:
Human
Cell Name:
SK-BR-3
Gene:
SENP7
Gene ID:
57337
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ448 |
|---|---|
| Product Name | SENP7 Knockout SK-BR-3 Cell Line |
| Cell Line | SK-BR-3 |
| NCBI Gene ID | |
| Cellosaurus ID | CVCL_0033 |
| Cell Line Synonyms | SK-Br-3, Sk-Br-3, SK BR 03, SKBR-3, SKBr-3, SK-BR3, SKBr3, SkBr3, SKBR3 |
| Gene | |
| Summary |
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]
|
| Associated Diseases | Breast Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: SK-BR-3 | STR Info (Cell bank) Cell Line: SK-BR-3 | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | X | ||
| CSF1PO | 12 | 12 | ||
| D2S1338 | 20 | 25 | 20 | 25 |
| D3S1358 | 17 | 17 | ||
| D5S818 | 9 | 12 | 9 | 12 |
| D7S820 | 9 | 12 | 9 | 12 |
| D8S1179 | 11 | 12 | 11 | 12 |
| D13S317 | 11 | 12 | 11 | 12 |
| D16S539 | 9 | 9 | ||
| D18S51 | 10 | 13 | 10 | 13 |
| D19S433 | 14 | 14 | ||
| D21S11 | 30 | 30.2 | 30 | 30.2 |
| FGA | 20 | 20 | ||
| Penta D | 9 | 12 | 9 | 12 |
| Penta E | 10 | 11 | 10 | 11 |
| TH01 | 8 | 9 | 8 | 9 |
| TPOX | 8 | 11 | 8 | 11 |
| vWA | 17 | 17 | ||
| D6S1043 | 11 | 19 | ||
| D12S391 | 18 | 20 | ||
| D2S441 | 13 | 14 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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