PDCD1 Knockout 786-O Cell Line
Cat.No.:
EDJ-KZ386
Species:
Human
Cell Name:
786-O
Gene:
PDCD1
Gene ID:
5133
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ386 |
|---|---|
| Product Name | PDCD1 Knockout 786-O Cell Line |
| Cell Line | 786-O |
| Cellosaurus ID | CVCL_1051 |
| Cell Line Synonyms | 786-o, 786O, 786-0, 786.O, 786-O RCC, RCC 786-O, RCC_7860, RCC 7860, 7860, 786-0WT |
| Gene | PDCD1 |
| NCBI Gene ID | |
| Gene Synonyms | ADMIO4|AIMTBS|CD279|PD-1|PD1|SLEB2|hPD-1|hPD-l|hSLE1 |
| Summary |
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
|
| Associated Diseases | Kidney Carcinoma |
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: 786-O | STR Info (Cell bank) Cell Line: 786-O | ||
| Allele1 | Allele2 | Allele1 | Allele2 | |
| Amelogenin | X | Y | X | Y |
| CSF1PO | 10 | 10 | ||
| D2S1338 | 17 | 18 | 17 | 18 |
| D3S1358 | 16 | 16 | ||
| D5S818 | 9 | 9 | ||
| D7S820 | 11 | 12 | 11 | 12 |
| D8S1179 | 13 | 13 | ||
| D13S317 | 8 | 8 | ||
| D16S539 | 12 | 12 | ||
| D18S51 | 13 | 14 | 13 | 14 |
| D19S433 | 14 | 15 | 14 | 15 |
| D21S11 | 29 | 30 | 29 | 30 |
| FGA | 24 | 24 | ||
| Penta D | 9 | 12 | 9 | 12 |
| Penta E | 7 | 16 | 7 | 16 |
| TH01 | 6 | 9.3 | 6 | 9.3 |
| TPOX | 8 | 11 | 8 | 11 |
| vWA | 15 | 17 | 15 | 17 |
| D6S1043 | 11 | |||
| D12S391 | 17 | 18 | ||
| D2S441 | 10 | 11 | ||
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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