PDCD1 Knockout NCI-H1299 Cell Line
Cat.No.:
EDJ-KZ387
Species:
Human
Cell Name:
NCI-H1299
Gene:
PDCD1
Gene ID:
5133
Size:
1×10⁶cells
| Cat.No. | EDJ-KZ387 |
|---|---|
| Product Name | PDCD1 Knockout H1299 Cell Line |
| Cell Line | NCI-H1299 |
| Cellosaurus ID | CVCL_0060 |
| Cell Line Synonyms | H1299, H-1299, NCIH1299 |
| Gene | PDCD1 |
| NCBI Gene ID | |
| Gene Synonyms | ADMIO4|AIMTBS|CD279|PD-1|PD1|SLEB2|hPD-1|hPD-l|hSLE1 |
| Summary |
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
|
| QC | Indels validated by Sanger sequencing; sterility confirmed via microbial testing. |
* For research use only. Not intended for use in humans or animals, including clinical, therapeutic, or diagnostic purposes.
| Loci | STR Info (Sample Cell) Sample Cell Line: NCI-H1299 | STR Info (Cell bank) Cell Line: NCI-H1299 | ||||
| Allele1 | Allele2 | Allele3 | Allele1 | Allele2 | Allele3 | |
| Amelogenin | X | X | ||||
| CSF1PO | 12 | 12 | ||||
| D5S818 | 11 | 11 | ||||
| D7S820 | 10 | 10 | ||||
| D13S317 | 12 | 12 | ||||
| D16S539 | 12 | 13 | 12 | 13 | ||
| TPOX | 8 | 8 | ||||
| vWA | 16 | 17 | 18 | 16 | 17 | 18 |
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.
Conclusion: The STR identification of this cell is correct.
* Research Use Disclaimer: Content is generated from publicly available research data, bioinformatic resources, and computational analyses for research reference only.
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